最近正好碰到这个问题，搜索论坛无果，自行谷歌解决了，方法如下：
Avid Knowledge Base
How To: Manually Uninstall Avid Audio Interface Driver Components (Mac OS X)
Last Updated : May 7, 2014
Products Affected : 003, 003_Rack, 003_Rack_Plus, Digi_002, Digi_002_Rack, Mbox_3rd_gen, Mbox_2, Mbox_2_Mini, Mbox_2_Pro
MBox 2
/System/library/extensions/digiDal.kext
/System/library/extensions/digiIO.kext
/System/library/extensions/DigidesignMbox2.kext
/System/library/extensions/DigidesignMbox2Boot.kext
/Users/username/Library/Preferences/com.digi.ptools.plist
/Users/username/Library/Preferences/DAE Prefs
/Users/username/Library/Preferences/DigiSetup.OSX
/Users/username/Library/Preferences/Pro Tools Prefs
/Library/Audio/Plug-Ins/HAL/DigidesignCoreAudio.plugin
/Library/Audio/MIDI Drivers/DigidesignMbox2MIDI.plugin
/Library/Startupitems/Digidesign Mbox2
/Library/Startupitems/DigidesignLoader
MBox (3rd Gen)
/Library/Extensions/DigidesignFirewireHelper
/Library/Frameworks/DigidesignFWDriver
/Library/LaunchAgents/com.avid.mbox.helper
/Library/LaunchDaemons/com.digidesign.FWFamily.helper
/Library/PreferencePanes/MBoxMini
/Library/PreferencePanes/AvidMBox.prefPane
/Library/Startupitems/anything Digidesign
/Library/Audio/MIDI Drivers/
Digi 002 & 003
/Library/Frameworks/DigidesignFWDriver
/Library/LaunchDaemons/firewire.helper.plist
/Library/LaunchDaemons/fwfamily.helper.plist
/Library/StartupItems/DigidesignLoader
/Library/Extensions/DigidesignFirewireHelper
/Library/Audio/MIDI Drivers/Digi/Avid files